Health supplements/routines to counter the adverse effects of drinking wine/alcohol

upregulates ALDH and ADH in the liver; has some effects in the gut as well.

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Not really a supplement… Age (of drinker not the wine!).

As I’ve gotten older I find I rarely get headache type hangovers. No controlled experiment alas so I don’t know if that’s increased wisdom in the quantity or variety of drinks consumed or some ageing physiology. I’m maybe more conscientious at drinking water as I go along.