Health supplements/routines to counter the adverse effects of drinking wine/alcohol

Shan_A · July 3, 2026, 2:13am

Mrkyl works better for my wife than me. Zbiotics works better for me than Myrkl, I thnk. My body also has a slight inflammatory reaction to Myrkl.

MChang · July 3, 2026, 2:24am

My regimen makes an enormous difference for my wearable data; the week before I was drinking just a couple glasses a night as we had friends visiting and I didn’t use any supplements and my readiness was toast. With a full prep my readiness is nearly normal and sleep is good.

Shan_A · July 3, 2026, 4:02pm

For me, I don’t feel 100% in the AM - but I feel much better and my ability and time to recovery is much better. No wearable data though, purely anecdotal

MChang · July 3, 2026, 5:09pm

While I think anecdotal experiences are useful and likely will inform purchase decisions for individuals I find wearable data far more compelling given the large potential placebo effect.

MChang · July 3, 2026, 11:47pm

I think the Myrkl is best used for a week preload.

Dan_A · July 4, 2026, 1:51pm

Any Myrkl offers?

Phil_T_r_o_t_t_e_r · July 4, 2026, 1:55pm

30% July 4th

MChang · July 4, 2026, 1:59pm

Click here and use code FREEDOM30 for 30% off Myrkl. (Affiliate code)

Dan_A · July 4, 2026, 2:07pm

Thanks!!

Sarah_Kirschbaum · July 4, 2026, 2:27pm

I hated it - happy to pass mine along for the cost of shipping.

Dan_A · July 4, 2026, 3:18pm

Thanks Sarah, I’d be happy to pay the shipping! This along with the Zbiotics seems to really work for me.

Albert_R · July 4, 2026, 4:30pm

I am still trying to figure out the best combo for me. Sometimes I get a headache when I take the supplements which I never get when I don’t take them.

Sarah_Kirschbaum · July 4, 2026, 4:33pm

DM me and we’ll figure it out.

LSYoung · July 8, 2026, 12:42am

For those so inclined, from Friday’s (2 July 2026) issue of Science:

Zhang, Y. et al. 2026. Zonated mechanosensing by PIEZO1 controls liver regeneration.

“Editor’s summary: Unlike most organs, the liver can regenerate and recover its original size after injury or surgery. The liver’s ability to determine when to regenerate and when to stop is linked to its sensing of physical forces such as tissue tension. Another distinctive feature of the liver is its zonation, division into functional zones based on the cells’ proximity to bile ducts and blood vessels and their access to supplies of nutrients and oxygen. By combining genetic and pharmacological approaches in multiple mouse models of liver injury, Zhang et al. identified a mechanism by which mechanical cues stimulate liver regeneration, as well as a connection with the liver’s functional zones, providing insights into the poorly understood process of zonated proliferation (see the Perspective by Maeso-Diaz and Diehl). — Yevgeniya Nusinovich”